Phenolphthalein White CAS: 77-09-8 | MF: C20H14O4 | MW: 318.32, Part Number I10557, Buy now for reliable and Reproducible results from Tristains indicators at Chemical World.
Phenolphthalein Indicator (WHITE) is a white colored powdered organic compound which belongs to the class of phthalein family. It is widely used as an acid-base indicating agent. Phenolphthalein is colorless in acidic solutions and turns pink to deep red in alkaline solutions. This chemical remains colourless below the pH value of 8.5 and attains a pink to deep red hue colour when the value of the pH is above 9.0. Phenolphthalein Indicator (WHITE)has a chemical formula of C20H14O4. It is sparingly soluble in water but soluble in alcohol and other organic solvents. Phenolphthalein is a chemical compound commonly used as a pH indicator and in various other applications.
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Application :
- Phenolphthalein indicator white is primarily used as a pH indicator. It changes color depending on the acidity or alkalinity of a solution. It is commonly used in acid-base titrations.
- It is frequently used in educational settings to demonstrate pH concepts and titration techniques due to its clear and easily observable color change.
Benefits :
- Provides a clear and distinct color change
- Sensitive and versatile
- Long shelf life and affordable
| Alternate Names | 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone |
| Application | Phenolphthalein is a commonly used colorimetric pH indicator |
| CAS Number | 77-09-8 |
| Molecular Weight | 318.32 |
| Molecular Formula | C20H14O4 |
Phenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. The compound has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12. It has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. The compound has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro. In Syrian hamster embryos treated with 10-40 ?M of Phenolpthalein a significant number of chromosomal aberrations occurred at the hprt locus. On human breast cancer cells Phenolphthalein has been observed to have weak estrogenic effects.
| Appearance | Powder |
| Physical State | Solid |
| Solubility | Soluble in water (partly), chloroform (slightly), acetone, ethanol (50 mg/ml), and methanol (10 mg/ml). |
| Storage | Store at room temperature |
| Melting Point | 261-263° C (lit.) |
| Boiling Point | ~557.8° C at 760 mmHg (Predicted) |
| Density | 1.30 g/cm3 at 20 |
| Refractive Index | n20D 1.69 (Predicted) |
| IC50 | GPR55: IC50 = 6.67 µM (human) |
| Ki Data | TS: Ki= 1.2 µM (human); Thymidylate synthase: Ki= 1.4 µM (Enterococcus faecalis); Thymidylate synthase: Ki= 4.7 µM (Escherichia coli K-12); Thymidylate synthase: Ki= 4.7 µM (Lactobacillus casei) |
| pK Values | pKa: 9.7 |
SAFETY INFORMATION
| WGK Germany | 3 |
| RTECS | SM8380000 |
| PubChem CID | 4764 |
| Merck Index | 14:7243 |
| MDL Number | MFCD00005913 |
| EC Number | 201-004-7 |
| Beilstein Registry | 284423 |
| SMILES | C1=CC=C2C(=C1)C(=O)OC2(C3=CC =C(C=C3)O)C4=CC=C(C=C4)O |
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