Pyronin Y Certified CAS: 92-32-0 | MF: C17H19N2O€š¬¢Cl | MW: 302.8S10160, Part Number S10160, Buy Histological Stains & Dyes for Histology, Cytology, Microbiology, Hematology & Biology Lab from TriStains at Chemical World.
.Pyronin Y is a synthetic dye belonging to the pyronin family of dyes. It is commonly used in various applications, including histology, microscopy, and as a biological stain.
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Alternate Names | Pyronin G, Pyronin J, Pyronin Y |
Application | Pyronin Y is a dye that intercalates and stains RNA red |
CAS Number | 92-32-0 |
Molecular Weight | 302.80 |
Molecular Formula: | C17H19N2O•Cl |
Pyronin Y is a dye that intercalates and stains RNA red, and has been shown to accumulate in the mitochondria of viable cells. Multidrug-resistant (MDR) Acinetobacter baumannii studies tested inhibition of the efflux pump by measuring the intracellluar accumulation of Pyronin Y and Ethidium bromide (sc-203947). Research shows that at low Pyronin Y concentrations the cytostatic effect is cell arrest in the G1 phase, whereas at high concentrations the cells arrest is in the G2 and S phase. Pyronin Y has been used in combination with Alcian Blue (sc-214517) to asses and study pulmonary diseases, and in combination with Methyl Green (sc-215348) to stain nucleic acids in paraffin sections. Additionally Pyronin Y has been used to measure RNA in flow cytometry.
Appearance | Powder |
Physical State | Solid |
Solubility | Soluble in water (30 mg/mL), methyl cellosolve (9 mg/mL), and ethanol (3 mg/mL). |
Storage | Store at room temperature |
Melting Point | 250-260° C (lit.) |
Density | 0.64 g/cm3 at 20 |
IC50 | HEK293 (Embryonic kidney fibroblasts): IC50 = 4540 nM (human) |
Fluoresence | ?ex 546 nm, ?em 565 nm in DMSO |
SAFETY INFORMATION
WGK Germany | 3 |
RTECS | BQ1450000 |
PubChem CID | 7085 |
Merck Index | 14: 8007 |
MDL Number | MFCD00011725 |
EC Number | 202-147-8 |
Beilstein Registry | 3795789 |
SMILES | CN(C)C1=CC2=C(C=C1)C=C3C=CC(=[N+](C)C)C=C3O2.[Cl-] |
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