Hematoxylin C.I. 75290 CAS: 517-28-2 | MF: - | MW: 302.28S10097, Part Number S10097, Buy Histological Stains & Dyes for Histology, Cytology, Microbiology, Hematology & Biology Lab from TriStains at Chemical World.
.Hematoxylin, also known as Hematoxylin cryst. (C.I. 75290), is a natural dye derived from the heartwood of the logwood tree (Haematoxylum campechianum). When combined with a mordant, such as aluminum, and oxidized to hematein, it becomes an effective staining agent for biological tissues. Its chemical formula is C16H14O6. Hematoxylin crystals are used as a dye for the specific staining of DNA in the nuclei. Widely utilized in histology and cytology, hematoxylin selectively stains cell nuclei, providing excellent contrast against the background. The stained nuclei appear blue, dark violet to black.
TriStains provides a marketplace for histology and biological stains, which is comprehensive enough to encompass the peculiar requirements of laboratories specializing in Histology, Cytology, Microbiology, and Hematology. With a reputation for exceeding quality expectations.
TriStains chromatic performance is outstanding which allows for resolution of cell and tissue components fundamental to life sciences to be clearly visualized. Each product under TriStains series is validated for accuracy, reliability and consistency. TriStains, which manufactures and markets stains and indicators in various packing, offers laboratories turn key solutions for all their staining and indicator needs, improving accuracy in every experiment.
Application :
- Hematoxylins are mixed with trivalent positively charged metal salts and build up the so-called hematoxylin lakes, used for the selective staining of nuclei (DNA) .
- The most common staining technique in histopathology, where hematoxylin stains cell nuclei blue or purple, and eosin stains the cytoplasm and extracellular matrix pink.
- Hematoxylin is a key component in the Pap stain, used for screening cervical cytology samples to detect abnormalities and malignancies.
- It is employed to stain Nissl bodies in neurons, aiding in the study of neuronal structure and pathology.
Benefits :
- High contrast and specific staining cell nuclei
- Versatile and very effective
- Cost-effective
| Alternate Names | Gills Hematoxylin Solution, No. 2 also known as Hematoxylin Gill II; Gills Formulation #2; CI 75290; Hydroxybraslin; Natural Black 1; Haematoxylin; (6aS,11bS)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,4,6a,9,10-pentol; GILL 2 METHOD HEMATOXYLIN STAIN; GILL HEMATOXYLIN SOLUTION NO II; GILL?S HEMATOXYLIN NO 2; GILL?S HEMATOXYLIN SOLUTION NO 2; GILLS II HAEMATOXYLIN; HEMATOXYLIN STAIN, GILL 2; HEMATOXYLIN SOLUTION GILL NO 2 |
| Application | Gill?s Hematoxylin Solution, No. 2 is a chromatin stain of blue-violet color used for both cytology and histology |
| CAS Number | 517-28-2 |
Gill?s Hematoxylin Solution, No. 2 is a chromatin stain used for both cytology and histology. Gill?s Hematoxylin Solution, No. 2 can be used for both progressive and regressive staining. Gill?s Hematoxylin Solution, No. 2 is of blue-violet color and is best used when more rapid staining is required.
| Formulation | A solution of hematoxylin in a mixture of water and ethylene glycol with acetic acid, aluminum sulfate, and sodium iodate. |
| Physical State | Liquid |
| Storage | Store at room temperature |
| pK Values | pKa: 9.16 (Predicted) |
| IC50 : | Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: IC50 = 5.23 µM (plasmodium berghei); Dengue virus type 2 NS3 protein: IC50 = 22.54 µM (dengue virus type 2 ) |
SAFETY INFORMATION
| Merck Index | 14: 4637 |
| MDL Number | MFCD00283323 |
| EC Number | 208-237-3 |
| Beilstein Registry : | 91399 |
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