Gallocyanine CAS: 1562-85-2 | MF: C15H13N2O5€š¬¢Cl | MW: 336.73S10093, Part Number S10093, Buy Histological Stains & Dyes for Histology, Cytology, Microbiology, Hematology & Biology Lab from TriStains at Chemical World.
.Gallocyanine, also known as 7-Dimethylamino-4-hydroxy-3-oxo-phenoxazine-1-carboxylic acid, is a synthetic dye classified under the oxazine class of dyes. Its chemical formula is C15H13ClN2O5. This dye is recognized for its deep blue to violet color and is commonly utilized in conjunction with chromium (gallocyanine-chrome alum) to improve its staining capabilities. The synthesis of gallocyanine involves the use of a methanol solution of gallic acid in the presence of excess iodine. It is predominantly employed in histological and cytological procedures to stain nucleic acids, creating a distinct contrast with the surrounding tissue.
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Application :
- Gallocyanine is used to stain Nissl bodies (granules of rough endoplasmic reticulum) in neurons, helping to visualize neuronal structures in brain and spinal cord tissues.
- Gallocyanine is used to stain animal cells,mostly the nucleic acids, making it useful for highlighting cell nuclei and chromosomes in tissue sections.
- It is used to stain cell nuclei in cytological preparations, aiding in the examination of cell morphology and pathology, also applied in various cytogenetic techniques to stain chromosomes for karyotyping and genetic studies.
- It is employed in the examination of tissue samples to identify and study abnormalities in cell and tissue structure.
- It is utilized in staining neuronal tissues to study the structure and organization of neurons and neural pathways.
- It also acts as a chelating agent and is used to determine bioactive compounds and several metal ions.
Benefits :
- Selective and precise staining of cell nuclei and chromosomes
- Produces high-contrast stains
- Versatile and stable
| Alternate Names | IIIC3; 7-Dimethylamino-4-hydroxy-3-oxo-phenoxazine-1-carboxylic acid; Mordant blue 10; C.I. 51030 |
| Application | Gallocyanine is a small molecule dye that also inhibits DKK1 of the Wnt pathway |
| CAS Number | 1562-85-2 |
| Molecular Weight | 336.73 |
| Molecular Formula: | C15H13N2O5•Cl |
Gallocyanine inhibits DKK1 of the Wnt pathway and acts as a small molecule dye.
| Appearance | Crystalline powder |
| Physical State | Solid |
| Solubility | Soluble in water (10 mg/ml), 100% ethanol (10 mg/ml), alcohol, 1N NH4OH (10 mg/ml), and DMSO (25 mg/ml). |
| Storage | Store at room temperature |
SAFETY INFORMATION
| WGK Germany | 3 |
| RTECS | SP7692000 |
| PubChem CID | 73801 |
| Merck Index | 14: 4355 |
| MDL Number | MFCD00011926 |
| EC Number | 216-345-7 |
| Beilstein Registry | 307454 |
| SMILES | CN(C)C1=CC2=C(C=C1)[NH+]=C3C(=CC(=O)C(=C3O2)O)C(=O)O.[Cl-] |
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