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Curcumin, C.I. 75300

Curcumin, C.I. 75300 CAS: 458-37-7 | MF: C21H20O6 | MW: 368.38, Buy now for reliable and reproducible results from Tristains at Chemical World.

The ingredient is Curcumin, C.I. 75300 (CAS No. 458-37-7), which is a plant-derived dye extracted from the turmeric plant. It forms a yellow-orange solution which is highly soluble in ethanol and dimethyl sulfoxide (DMSO), but is insoluble in water. The chemical equation of Curcumin is C21H20O6. It is also known as diferuloylmethane, diferulylmethane, Natural Yellow 3, and by its systematic chemical name (E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione. In biological and analytical laboratory work, curcumin (CI 75300) is very common as a stain and indicator

Applications

  • Curcumin is another widely applied in histological and cytological staining of cells and tissues to visualize them better.
  • It is also used as a complexometric measure of boron, forming a red-colored complex of rosocyanine on reaction with boric acid.

Key features

  • Stable and dependable outcomes: Gives reliable performance in the staining processes as well as the analytical chemistry.
  • Anti-Inflammatory Activity: Shows biological interest and is frequently investigated in biochemical and pharmacological studies.
  • Cost-effective and easy to use: Inexpensive and is easily integrated in most laboratory procedures.

General Description

Curcumin (CAS No. 458-37-7), having a molecular formula C21H20O6 and a molecular weight of 368.38 g/mol, is a yellow-orange natural colorant which belongs to Natural Yellow 3 and CI 75300. It is a polyphenolic molecule that is extracted from the rhizome of turmeric and has become of great importance in laboratory and scientific practice because of its staining, analytical, and bioactive properties.

Chemical World offers high-purity Curcumin that can be used in scientific, analytical, and research services. It is produced and tested for quality to comply with the laboratory standards and delivered in a safe packaging that allows the maintenance of stability and integrity. Curcumin is offered at reasonable prices and is affordable to educational institutions, research laboratories, and industries. Customers can request a quotation or make orders online to get up-to-date prices, packaging choices or quantities to be ordered, etc.

About Brand

TriStains provides a marketplace for histology and biological stains, which is comprehensive enough to encompass the peculiar requirements of laboratories specializing in Histology, Cytology, Microbiology, and Hematology. With a reputation for exceeding quality expectations, TriStains performance is outstanding, which allows for the resolution of cell and tissue components fundamental to life sciences to be clearly visualized. Each product under the TriStains series is validated for accuracy, reliability, and consistency. TriStains, which manufactures and markets stains and indicators in various packaging, offers laboratories turnkey solutions for all their staining and indicator needs, improving accuracy in every experiment.

Chemical World provides the best laboratory brands that provide a constant and reliable result for any kind of experiment. Our range of high-quality laboratory brands is complete and is available in various scientific fields. ChemieR supplies high-purity chemicals to be used in reliable laboratories, cUSP supplies certified and standard solutions which can be used right away to assess accurately, and TriStains provides high-quality histological stains and indicators to be used in order to visualize accurately. LiChrom is the provider of liquid chromatography using high-grade reagents, and Bluster is the provider of high-grade solvents used in gas chromatography. EKS focuses on electronics-grade reagents that are used in advanced and sensitive analysis. These brands assure the research, analytical, and industrial laboratories with trusted quality, consistency, and performance. To get your product details, specifications, or to seek any purchasing assistance, visit our site chemicalworlds.com or email our sales team sales@chemicalworlds.com. We are happy to service your laboratory requirements with professional and fast service.

Application À Ã„ÂÆ’¬Ã€¦¡ Curcumin is a yellow-orange dye, NOS2 regulator, and inhibitor of NF-B, 5-LO, Cox-2, COP9, and p300/CBP.
CAS Number 458-37-7
Purity 95%
Molecular Weight 368.38
Molecular Formula À Ã„ÂÆ’¬Ã€¦¡ C21H20O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. Refer to Certificate of Analysis for lot specific data (including water content).Curcumin is a yellow-orange dye obtained from tumeric, the powdered root of Curcuma longa. Curcumin is employed in the preparation of curcuma paper, the detection of boron, and possesses a vast number of biological targets. Curcumin has been shown to inhibit NF-B, possibly through inhibition of JNK (IC50=10 M). Curcumin blocks amyloid peptide induced expression of: TNF-, IL-1, MCP-1, IL-8, and CCR5, regulates NOS2, inhibits IgE and Ag-induced degranulation of mast cells, inhibits 5-LO (5-lipoxygenase) (IC50=8 M), Cox-2 (cyclooxygenase-2) (IC50=52 M), the COP9 signalosome kinase (IC50=10 ,µM), and p300/CBP. This wide range of activities makes Curcumin an extremely useful tool for developing novel analogues and uses.
Appearance : Powder
Physical State : Solid
Solubility : Soluble in water (1 mg/ml), and ethanol (1%). Insoluble in acetone.
Derived From : Turmeric rhizome
Solubility : Soluble in DMSO (25 mg/ml), acetic acid, 0.1M NaOH, 10mM Na2CO3, acetone, water (< 0.1 mg/ml), and chloroform. Insoluble in ethanol.
Storage : Store at room temperature
Melting Point : 170-175,° C
Boiling Point : ~591.4,° C at 760 mmHg (Predicted)
Density : ~1.3 g/cm3 (Predicted)
Refractive Index : n20D 1.42
IC50 : 5-lipoxygenase: IC50 = 8 ,µM; cyclooxygenase: IC50 = 52 ,µM; nitric oxide synthase in activated macrophages: IC50 = 6 ,µM

SAFETY INFORMATION

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

WGK Germany : 3
PubChem CID :
969516
RTECSÀ Ã„ÂÆ’¬Ã€¦¡ :
MI5230000
Merck Index :
14: 2673
MDL Number :
MFCD00008365
EC Number :
207-280-5
Beilstein Registry :
2306965
SMILES :
COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

Safety Data Sheets (SDS), Product Specification (PS) and Certificates of Analysis (COA) click Document Button